Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.) Schrad. methanolic fruit extract

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Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.) Schrad. methanolic fruit extract.

Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) is a medicinal plant traditionally used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes. Preliminary phytochemical screening of the plant showed the presence of large amounts of phenolics and flavonoids. Subsequent quantification showed the presence of 0.74% (m/m) phenolics (calculated as gallic ...

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Antimicrobial Activity of the Methanolic Extract, Fractions and Isolated Compounds from Citrullus Colocynthis (l.) Schrad

The methanolic crude extract prepared from the fruits of Citrullus colocynthis (MCCF), its fractions and two isolated compounds namely Ursolic Acid, (compound1) and Cucurbitacin E 2-0-β-D-glucopyranoside (compound 2) were evaluated for their antibacterial activity. Broth microdilution and agar disc diffusion methods were used for the investigations. The antimicrobial assays showed that the crud...

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Cucurbitacins from the Leaves of Citrullus colocynthis (L.) Schrad.

Two new tetracyclic cucurbitane-type triterpene glycosides were isolated from an ethyl acetate extract of Citrullus colocynthis leaves together with four known cucurbitacins. Their structures were established on the basis of their spectroscopic data (mainly NMR and mass spectrometry). Evaluation of the in vitro cytotoxic activity of the isolated compounds against two human colon cancer cell lin...

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Biomedical potential of silver nanoparticles synthesized from calli cells of Citrullus colocynthis (L.) Schrad

BACKGROUND An increasingly common application is the use of silver nanoparticles for antimicrobial coatings, wound dressings, and biomedical devices. In this present investigation, we report, biomedical potential of silver nanopaticles synthesized from calli extract of Citrullus colocynthis on Human epidermoid larynx carcinoma (HEp -2) cell line. METHODS The callus extract react with silver n...

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Anti-inflammatory and analgesic activities of Tunisian Citrullus colocynthis Schrad. immature fruit and seed organic extracts.

BACKGROUND AND OBJECTIVES Inflammations and immune-related diseases including rheumatoid arthritis are widespread in the entire globe. The treatment of these illnesses is mainly based on the use of synthetic and biotechnological drugs, in recent years. Tunisian traditional medicine is a potential source of new remedies namely Citrullus colocynthis Schrad. (Cucurbitaceae): endemic in southern Tu...

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ژورنال

عنوان ژورنال: Acta Pharmaceutica

سال: 2008

ISSN: 1846-9558,1330-0075

DOI: 10.2478/v10007-008-0008-1